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Belgium 23-6-26 All Members Physical english
Sourcing for Autonomy, Resilience and Competitive Advantage. Global platforms offer incredible speed and innovation, but they also create deep dependencies that can expose your business to vendor lock-in, supply chain disruptions, and regulatory shifts. For today's CIO, the central challenge is no longer just about technology adoption; it's about building a digital foundation that is both agile and resilient. Strategic sourcing is the key. It has evolved from a procurement function into the primary tool for CIOs to navigate uncertainty, mitigate risk, and achieve digital autonomy. This session provides a practical playbook for using strategic sourcing to build a future-proof enterprise.
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Belgium 30-6-26 Public Physical french
L'IT Public au point de rupture : Vers un modèle à l'usage ? Transformer l'inertie en agilité : le défi du service public. Le constat : L’ère de la possession touche à sa fin Le citoyen n'attend pas que vous gériez des serveurs ; il attend des services. Pourtant, le modèle IT public reste prisonnier du « faire » plutôt que du « résultat ». Entre des budgets CAPEX verrouillés sur 5 ans et des cycles de procurement qui naissent périmés, l'écart se creuse. Le dilemme est stratégique : Comment passer d'une infrastructure que l'on subit à une informatique pilotée par le résultat (Outcome-based IT) ? Est-il possible d'adopter la souplesse du Cloud sans abandonner les clés de notre souveraineté ? L'objet du débat : Le "As-a-Service" au-delà du concept Nous vous invitons à remettre en question les promesses des modèles orientés vers la consommation. L'objectif est de débattre, sans tabou, du potentiel réel de ces approches pour le secteur public : Inverser la responsabilité : Passer de l'achat de matériel à l'achat de niveaux de service (SLA). Est-ce le secret pour libérer vos équipes de la maintenance ? Aligner le coût sur l'usage : En finir avec le surprovisionnement pour ne payer que ce qui est réellement consommé. Agilité "Procurement-proof" : Comment le modèle à l'usage permet-il de scaler en quelques jours ce qui prenait des mois d'appels d'offres ? La souveraineté par le contrat : Le "As-a-Service" sur site est-il le compromis idéal entre contrôle privé et flexibilité publique ? Le Format : "Zero Slides, Full Insight" Pas de présentation ni de marketing, uniquement une confrontation de visions entre pairs : Cercle restreint : Décideurs du secteur public francophone. Règle de Chatham House : Ce qui se dit à table reste à table. Débat pur : Une discussion structurée autour de vos doutes et de vos ambitions numériques.
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Belgium 30-6-26 All Members Physical english
As AI becomes critical to business success, organisations in highly regulated sectors such as Financial Services, Critical Infrastructures and Defence, face strict data privacy, security, and compliance mandates that make public cloud AI a non-starter. This interactive session will explore the practical realities, both the benefits and limitations, of bringing enterprise-grade AI capabilities directly onto your own premises. Join CIONET, Kyndryl, and Dell Technologies for an exclusive, hands-on roundtable and live workshop on navigating the crucial intersection of artificial intelligence, data sovereignty, and autonomous operations. We will move beyond the theory by bringing the physical machine into the room for a live, air-gapped demonstration of cutting-edge workloads running entirely on-site. This interactive workshop will bring together Digital Leaders to: Demystify Sovereign AI at the C-Level: Review the strategic trade-offs, architecture, and compliance advantages of running localised AI models. See Zero-Leak Secure Code Review in Action: Watch a live demo of an on-premise LLM scanning software for vulnerabilities, ensuring your codebase never leaves your secure infrastructure. Experience On-Premise Agentic AI: Witness a local, autonomous monitoring agent, utilising advanced, Claude-level reasoning capabilities, managing critical IT Operations tasks completely offline. Collaborate on Best Practices: Engage with peers to discuss deployment timelines, security frameworks, and infrastructure requirements for true data control. Don't miss this opportunity to interact with live hardware, engage with industry peers, and gain actionable insights into unleashing the power of sovereign and agentic AI.
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CIONET Trailblazer: CISO: The Shift from Prevention to Resilience: Turning Visibility into Execution
Published on: January 28, 2026 @ 9:48 AM
CIONET Trailblazer: AI Transformation: Bridging the Cultural Divide to Achieve Competitive Advantage
Published on: December 17, 2025 @ 9:16 AM
Exscientia Uses Generative AI to Reimagine Drug Discovery
Exscientia uses generative artificial intelligence (AI) throughout the design-make-test-learn (DMTL) cycle to discover new therapies for patients quickly and relatively inexpensively.
“Using AWS, we reduce bottlenecks and accelerate the pipeline.”
David Hallett
Interim CEO and Chief Scientific Officer, Exscientia

Exscientia uses generative artificial intelligence (AI) throughout the design-make-test-learn (DMTL) cycle to discover new therapies for patients quickly and relatively inexpensively. Conventional drug discovery methods can take up to 15 years and cost over 2 billion dollars, with an average failure rate of 90–96 percent because scientists hunt for specific drug candidates among 1060 bioavailable small molecules.
Built on Amazon Web Services (AWS), Exscientia’s innovative DMTL solution incorporates in silico design—using generative AI algorithms to design compounds in the cloud—and automated robots that make drug candidates in a lab. “We use generative AI to solve for efficiency and effectiveness,” says David Hallett, Exscientia’s interim CEO and chief scientific officer. “By predicting the molecular features of a safe and effective drug in silico, we minimize the number of costly experiments. Our platform, built in collaboration with the AWS team, is optimized for speed. We can repeat many DMTL learning loops, improving our drug candidates with every iteration.”
Working backward from patient needs, Exscientia defines precise target product profiles (TPPs) that specify the complex combination of properties required by a well-tolerated and effective medicine. AI engineers design algorithms that generate panels of potential drug candidates to meet the TPPs. Active learning algorithms help expert designers to select a short list of drug candidates to synthesize in the lab, because they either move the TPPs forward or refine the models for future DMTL cycles.
Exscientia’s algorithms are trained on publicly available pharmacology data and proprietary in-house data generated from patient tissue samples, genomics, single-cell transcriptomics, and medical literature. By encoding data throughout the process and analyzing experimental results and previous design cycles, Exscientia can optimize upcoming design cycles and promote compound designs that are physically synthesizable. Using this synthesis-aware, iterative approach built on AWS, Exscientia makes 10 times fewer compounds than the industry average. “The idea is to iron out chemical liabilities to make safer and more effective drug candidates before we ever test them in patients,” says Hallett.
Exscientia has accelerated drug design by up to 70 percent while decreasing capital cost by 80 percent, compared with industry benchmarks. Using generative AI with other tools, Exscientia not only developed better drug candidates faster but also identified the right drug combinations to trial with patients in the clinic.
Exscientia has incorporated cutting-edge chemistry synthesis and biology assay lab equipment with automation robots to avoid manual handling of lab equipment. Thus, its lab—orchestrated by AWS microservices—can operate 24/7 with minimal human supervision, “When our designs are ready, we can push a button, and within a few days, the robots are making the drug,” says Hallett. Maintaining extremely high levels of security and comprehensive disaster recovery, Exscientia will use this automated robotic capability to reduce the make and test timelines resulting from traditional offshore research contracts used across the industry.
As the company closes the loop with its robotic automation lab, it expects further productivity improvements. Data generated in the lab improves algorithmic predictions and speeds up DMTL cycles.
Six molecules that Exscientia designed using AI have entered clinical trials. “Using AWS, we reduce bottlenecks and accelerate the pipeline,” says Hallett. “By switching on this highly integrated and automated DMTL loop, we can make drug candidates faster and more cost-effective.”
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CIONET’s Cyber Circle: a new three-event programme exclusively focusing on the most urgent, complex, and high-impact challenges in cybersecurity today. Launched in 2026, this initiative brings together CISOs, CIOs, and senior IT executives with a strong interest in cybersecurity for three curated gatherings each year. As part of CIONET’s trusted executive community, the Cyber Circle provides a confidential, peer-driven environment to exchange insights, share real-world experiences, and address evolving cyber threats. Each session is designed to foster strategic dialogue, strengthen resilience, and elevate cybersecurity as a core driver of business value.
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The Telenet Business Leadership Circle powered by CIONET, offers a platform where IT executives and thought leaders can meet to inspire each other and share best practices. We want to be a facilitator who helps you optimise the performance of your IT function and your business by embracing the endless opportunities that digital change brings.
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Découvrez la dynamique du leadership numérique aux Rencontres de CIONET, le programme francophone exclusif de CIONET pour les leaders numériques en Belgique, rendu possible grâce au soutien et à l'engagement de nos partenaires de programme : Deloitte, Denodo et Red Hat. Rejoignez trois événements inspirants par an à Liège, Namur et en Brabant Wallon, où des CIOs et des experts numériques francophones de premier plan partagent leurs perspectives et expériences sur des thèmes d'affaires et de IT actuels. Laissez-vous inspirer et apprenez des meilleurs du secteur lors de sessions captivantes conçues spécialement pour soutenir et enrichir votre rôle en tant que CIO pair. Ne manquez pas cette opportunité de faire partie d'un réseau exceptionnel d'innovateurs numériques !
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CIONET is committed to highlighting and celebrating female role models in IT, Tech & Digital, creating a leadership programme that empowers and elevates women within the tech industry. This initiative is dedicated to showcasing the achievements and successes of leading women, fostering an environment where female role models are recognised, and their contributions can ignite progress and inspire the next generation of women in IT. Our mission is to shine the spotlight a little brighter on female role models in IT, Tech & Digital, and to empower each other through this inner network community.
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