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Belgium 21-10-25 Squad Only Physical english

AI in Practice ; What it really takes to move from pilot to production

Every organisation has a handful of AI pilots. But very few have scaled them. The models are accurate. The vision is clear. But something’s always in the way; lack of infrastructure, unclear ownership, security concerns, or just plain fatigue. This is a conversation for people in the messy middle of the AI journey, those navigating the leap from promising prototypes to operational value.

Belgium 21-10-25 Invitation Only Physical english

CIONET Round Table - From Disconnected Data to Unified Insight ; Building a 360° customer view to unlock commercial growth

In today's competitive landscape, customer expectations have never been higher. They demand a personalised, seamless experience at every touchpoint, from initial marketing contact to post-sale service. Unified data is at the heart of creating engaging customer experiences and is meant to fuel the 360 profile. However, for many organizations, a complete picture of the customer is fragmented, with critical data scattered in disconnected systems and departments. This exclusive roundtable will bring together Digital Leaders active in multiple industries to discuss a critical challenge: breaking down data silos to build a true 360° view of the customer. We will explore how to solve the complex integration challenges that prevent a unified view, and how to transform disparate data into a single source of truth. Join us to: Discover how to overcome the technical hurdles of integrating critical business systems, such as ERP and CRM platforms, to unify customer data. Explore real-world case studies on how organisations have successfully created unified customer insights to enhance personalisation and boost commercial and operational efficiency. Discuss best practices for turning fragmented data into actionable insights that can anticipate customer needs, drive revenue growth, and foster long-term loyalty. This is a unique opportunity for Digital Leaders who are ready to transform their customer engagement strategy and unlock the full potential of their data.

Belgium 22-10-25 Invitation Only Physical english

The End of the Firewall

Enterprises are questioning whether private networks and stacked firewalls are still worthwhile investments. A newer approach operates on the open internet with Zero Trust, eliminates perimeter complexity, and reframes cybersecurity as a business performance metric for boards and audit committees. This is a closed-door, peer discussion, not a lecture. We’ll examine the promise and its pitfalls: Are the promised savings significant, or are they too good to be true? What risks do you introduce? How does this collide with your installed base, legacy OT, entrenched processes and team competencies, and how do you overcome that without breaking operations or credibility with the board? Two senior leaders from global companies will spark the dialogue with lived experience: Kurt De Ruwe, CIO AkzoNobel Frank Bolata, CIO Syensqo

October 21, 2025 Squad Session Squad Only Physical english

AI in Practice ; What it really takes to move from pilot to production

November 4, 2025 Squad Session Squad Only Virtual english

From Backlog to Value ; Prioritising what matters when everything feels urgent

You’ve got a roadmap, a backlog, and a lot of pressure. Every team wants their feature. Every stakeholder claims urgency. And your developers? They just want to deliver something meaningful. But how do you prioritise in a way that serves the business, and keeps the team sane? If your backlog keeps growing and your outcomes stay flat, this session helps you turn intent into value, without losing control.

November 18, 2025 Squad Session Squad Only Physical english

Business Process Driven Architecture ; Designing systems that follow how your organisation actually works

Too often, architecture is drawn top-down, neat boxes, elegant flows, and little connection to the way teams really work. But what if we flipped it? What if our systems evolved from the actual processes, pains, and needs that drive the business? If you’re tired of systems that look good on slides but frustrate in practice, this session will ground the conversation where value is created, at the process level.

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Exscientia Uses Generative AI to Reimagine Drug Discovery

Exscientia uses generative artificial intelligence (AI) throughout the design-make-test-learn (DMTL) cycle to discover new therapies for patients quickly and relatively inexpensively.

“Using AWS, we reduce bottlenecks and accelerate the pipeline.”

David Hallett
Interim CEO and Chief Scientific Officer, Exscientia

Exscientia uses generative artificial intelligence (AI) throughout the design-make-test-learn (DMTL) cycle to discover new therapies for patients quickly and relatively inexpensively. Conventional drug discovery methods can take up to 15 years and cost over 2 billion dollars, with an average failure rate of 90–96 percent because scientists hunt for specific drug candidates among 10⁶⁰ bioavailable small molecules.

Built on Amazon Web Services (AWS), Exscientia’s innovative DMTL solution incorporates in silico design—using generative AI algorithms to design compounds in the cloud—and automated robots that make drug candidates in a lab. “We use generative AI to solve for efficiency and effectiveness,” says David Hallett, Exscientia’s interim CEO and chief scientific officer. “By predicting the molecular features of a safe and effective drug in silico, we minimize the number of costly experiments. Our platform, built in collaboration with the AWS team, is optimized for speed. We can repeat many DMTL learning loops, improving our drug candidates with every iteration.”

Using Generative AI for More Efficient Drug Discovery at Reduced Cost

Working backward from patient needs, Exscientia defines precise target product profiles (TPPs) that specify the complex combination of properties required by a well-tolerated and effective medicine. AI engineers design algorithms that generate panels of potential drug candidates to meet the TPPs. Active learning algorithms help expert designers to select a short list of drug candidates to synthesize in the lab, because they either move the TPPs forward or refine the models for future DMTL cycles.

Exscientia’s algorithms are trained on publicly available pharmacology data and proprietary in-house data generated from patient tissue samples, genomics, single-cell transcriptomics, and medical literature. By encoding data throughout the process and analyzing experimental results and previous design cycles, Exscientia can optimize upcoming design cycles and promote compound designs that are physically synthesizable. Using this synthesis-aware, iterative approach built on AWS, Exscientia makes 10 times fewer compounds than the industry average. “The idea is to iron out chemical liabilities to make safer and more effective drug candidates before we ever test them in patients,” says Hallett.

Exscientia has accelerated drug design by up to 70 percent while decreasing capital cost by 80 percent, compared with industry benchmarks. Using generative AI with other tools, Exscientia not only developed better drug candidates faster but also identified the right drug combinations to trial with patients in the clinic.

Cutting Time and Costs Using Automated Robotics to Make Better Medicines

Exscientia has incorporated cutting-edge chemistry synthesis and biology assay lab equipment with automation robots to avoid manual handling of lab equipment. Thus, its lab—orchestrated by AWS microservices—can operate 24/7 with minimal human supervision, “When our designs are ready, we can push a button, and within a few days, the robots are making the drug,” says Hallett. Maintaining extremely high levels of security and comprehensive disaster recovery, Exscientia will use this automated robotic capability to reduce the make and test timelines resulting from traditional offshore research contracts used across the industry.

As the company closes the loop with its robotic automation lab, it expects further productivity improvements. Data generated in the lab improves algorithmic predictions and speeds up DMTL cycles.

Introducing AI-Designed Molecules into Clinical Trials

Six molecules that Exscientia designed using AI have entered clinical trials. “Using AWS, we reduce bottlenecks and accelerate the pipeline,” says Hallett. “By switching on this highly integrated and automated DMTL loop, we can make drug candidates faster and more cost-effective.”

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Healthcare Circle

Digital Transformation is redefining the future of health care and health delivery. All stakeholders are convinced that these innovations will create value for patients, healthcare practitioners, hospitals, and governments along the patient pathway. The benefits are starting from prevention and awareness to diagnosis, treatment, short- and long-term follow-up, and ultimately survival. But how do you make sure that your working towards an architecturally sound, secure and interoperable health IT ecosystem for your hospital and avoid implementing a hodgepodge of spot solutions? How does your IT department work together with the other stakeholders, such as the doctors and other healthcare practitioners, Life Sciences companies, Tech companies, regulators and your internal governance and administrative bodies?

Telenet Business Leadership Circle

The Telenet Business Leadership Circle powered by CIONET, offers a platform where IT executives and thought leaders can meet to inspire each other and share best practices. We want to be a facilitator who helps you optimise the performance of your IT function and your business by embracing the endless opportunities that digital change brings.

Les Rencontres

Découvrez la dynamique du leadership numérique aux Rencontres de CIONET, le programme francophone exclusif de CIONET pour les leaders numériques en Belgique, rendu possible grâce au soutien et à l'engagement de nos partenaires de programme : Deloitte, Denodo et Red Hat. Rejoignez trois événements inspirants par an à Liège, Namur et en Brabant Wallon, où des CIOs et des experts numériques francophones de premier plan partagent leurs perspectives et expériences sur des thèmes d'affaires et de IT actuels. Laissez-vous inspirer et apprenez des meilleurs du secteur lors de sessions captivantes conçues spécialement pour soutenir et enrichir votre rôle en tant que CIO pair. Ne manquez pas cette opportunité de faire partie d'un réseau exceptionnel d'innovateurs numériques !

Female Leadership Circle

CIONET is committed to highlighting and celebrating female role models in IT, Tech & Digital, creating a leadership programme that empowers and elevates women within the tech industry. This initiative is dedicated to showcasing the achievements and successes of leading women, fostering an environment where female role models are recognised, and their contributions can ignite progress and inspire the next generation of women in IT. Our mission is to shine the spotlight a little brighter on female role models in IT, Tech & Digital, and to empower each other through this inner network community.