Belgium 30-9-25 Squad Only Virtual english
Everyone has technical debt. The question is what to do with it. Refactor now? Wait for the next feature? Build on it and hope it holds? If you’re tired of debating whether to clean up or move on, this session helps you frame the debt conversation in a way that supports both speed and stability.
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Belgium 1-10-25 Invitation Only Physical english
In today’s rapidly evolving technological landscape, organisations face a critical challenge: how to modernise their legacy systems while managing costs, maintaining security, and ensuring operational continuity. This exclusive round table discussion brings together CIOs, CTOs, and Digital Leaders to explore best practices for legacy and lifecycle management. Key topics include extending the lifespan of existing systems, mitigating cyber security risks, optimising costs, and integrating legacy platforms with modern technologies. We’ll also delve into sustainability, workforce challenges, and future-proofing IT infrastructures to navigate technological obsolescence.
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Belgium 2-10-25 Squad Only Virtual english
Architecture doesn’t happen in diagrams. It happens in minds, seasoned, curious, sharp minds that understand how the pieces fit. But who’s shaping these minds? Who’s growing the next generation of digital architects? If you’re responsible for complex systems, and for the people designing them, this session is for you.
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September 30, 2025 Squad Session Squad Only Virtual english
Everyone has technical debt. The question is what to do with it. Refactor now? Wait for the next feature? Build on it and hope it holds? If you’re tired of debating whether to clean up or move on, this session helps you frame the debt conversation in a way that supports both speed and stability.
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October 2, 2025 Squad Session Squad Only Virtual english
Architecture doesn’t happen in diagrams. It happens in minds, seasoned, curious, sharp minds that understand how the pieces fit. But who’s shaping these minds? Who’s growing the next generation of digital architects? If you’re responsible for complex systems, and for the people designing them, this session is for you.
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October 14, 2025 Squad Session Squad Only Virtual english
Agile delivery often collides with inflexible infrastructures. One team wants to release weekly. Another is waiting six months for a new test environment. Sounds familiar? If your infra team is tired of being the bottleneck, and your devs are tired of waiting, this session opens a path forward.
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Exscientia Uses Generative AI to Reimagine Drug Discovery
Exscientia uses generative artificial intelligence (AI) throughout the design-make-test-learn (DMTL) cycle to discover new therapies for patients quickly and relatively inexpensively.
“Using AWS, we reduce bottlenecks and accelerate the pipeline.”
David Hallett
Interim CEO and Chief Scientific Officer, Exscientia
Exscientia uses generative artificial intelligence (AI) throughout the design-make-test-learn (DMTL) cycle to discover new therapies for patients quickly and relatively inexpensively. Conventional drug discovery methods can take up to 15 years and cost over 2 billion dollars, with an average failure rate of 90–96 percent because scientists hunt for specific drug candidates among 1060 bioavailable small molecules.
Built on Amazon Web Services (AWS), Exscientia’s innovative DMTL solution incorporates in silico design—using generative AI algorithms to design compounds in the cloud—and automated robots that make drug candidates in a lab. “We use generative AI to solve for efficiency and effectiveness,” says David Hallett, Exscientia’s interim CEO and chief scientific officer. “By predicting the molecular features of a safe and effective drug in silico, we minimize the number of costly experiments. Our platform, built in collaboration with the AWS team, is optimized for speed. We can repeat many DMTL learning loops, improving our drug candidates with every iteration.”
Working backward from patient needs, Exscientia defines precise target product profiles (TPPs) that specify the complex combination of properties required by a well-tolerated and effective medicine. AI engineers design algorithms that generate panels of potential drug candidates to meet the TPPs. Active learning algorithms help expert designers to select a short list of drug candidates to synthesize in the lab, because they either move the TPPs forward or refine the models for future DMTL cycles.
Exscientia’s algorithms are trained on publicly available pharmacology data and proprietary in-house data generated from patient tissue samples, genomics, single-cell transcriptomics, and medical literature. By encoding data throughout the process and analyzing experimental results and previous design cycles, Exscientia can optimize upcoming design cycles and promote compound designs that are physically synthesizable. Using this synthesis-aware, iterative approach built on AWS, Exscientia makes 10 times fewer compounds than the industry average. “The idea is to iron out chemical liabilities to make safer and more effective drug candidates before we ever test them in patients,” says Hallett.
Exscientia has accelerated drug design by up to 70 percent while decreasing capital cost by 80 percent, compared with industry benchmarks. Using generative AI with other tools, Exscientia not only developed better drug candidates faster but also identified the right drug combinations to trial with patients in the clinic.
Exscientia has incorporated cutting-edge chemistry synthesis and biology assay lab equipment with automation robots to avoid manual handling of lab equipment. Thus, its lab—orchestrated by AWS microservices—can operate 24/7 with minimal human supervision, “When our designs are ready, we can push a button, and within a few days, the robots are making the drug,” says Hallett. Maintaining extremely high levels of security and comprehensive disaster recovery, Exscientia will use this automated robotic capability to reduce the make and test timelines resulting from traditional offshore research contracts used across the industry.
As the company closes the loop with its robotic automation lab, it expects further productivity improvements. Data generated in the lab improves algorithmic predictions and speeds up DMTL cycles.
Six molecules that Exscientia designed using AI have entered clinical trials. “Using AWS, we reduce bottlenecks and accelerate the pipeline,” says Hallett. “By switching on this highly integrated and automated DMTL loop, we can make drug candidates faster and more cost-effective.”
Digital Transformation is redefining the future of health care and health delivery. All stakeholders are convinced that these innovations will create value for patients, healthcare practitioners, hospitals, and governments along the patient pathway. The benefits are starting from prevention and awareness to diagnosis, treatment, short- and long-term follow-up, and ultimately survival. But how do you make sure that your working towards an architecturally sound, secure and interoperable health IT ecosystem for your hospital and avoid implementing a hodgepodge of spot solutions? How does your IT department work together with the other stakeholders, such as the doctors and other healthcare practitioners, Life Sciences companies, Tech companies, regulators and your internal governance and administrative bodies?
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The Telenet Business Leadership Circle powered by CIONET, offers a platform where IT executives and thought leaders can meet to inspire each other and share best practices. We want to be a facilitator who helps you optimise the performance of your IT function and your business by embracing the endless opportunities that digital change brings.
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Découvrez la dynamique du leadership numérique aux Rencontres de CIONET, le programme francophone exclusif de CIONET pour les leaders numériques en Belgique, rendu possible grâce au soutien et à l'engagement de nos partenaires de programme : Deloitte, Denodo et Red Hat. Rejoignez trois événements inspirants par an à Liège, Namur et en Brabant Wallon, où des CIOs et des experts numériques francophones de premier plan partagent leurs perspectives et expériences sur des thèmes d'affaires et de IT actuels. Laissez-vous inspirer et apprenez des meilleurs du secteur lors de sessions captivantes conçues spécialement pour soutenir et enrichir votre rôle en tant que CIO pair. Ne manquez pas cette opportunité de faire partie d'un réseau exceptionnel d'innovateurs numériques !
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CIONET is committed to highlighting and celebrating female role models in IT, Tech & Digital, creating a leadership programme that empowers and elevates women within the tech industry. This initiative is dedicated to showcasing the achievements and successes of leading women, fostering an environment where female role models are recognised, and their contributions can ignite progress and inspire the next generation of women in IT. Our mission is to shine the spotlight a little brighter on female role models in IT, Tech & Digital, and to empower each other through this inner network community.
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